For Investigators. 2012 nPOD Annual Meeting Presentations for Distribution
In order to view any of ther presentations below, you must be an approved nPOD investigator and you will need to input the username and password distributed to you for the purpose of viewing investigator documents.
Session 1: Viral Etiology
Title: Replication Defective Enterovirus Infections: Implications for Type 1 Diabetes
Presenter: Nora Chapman
Title: Detection of Enteroviruses in Tissue Samples of Cadaveric Organ Donors with Type 1 Diabetes
Presenter: Heikki Hyöty
Title: Detection of Enteroviral Proteins and Cellular Antiviral Responses in the Islets of Type 1 Diabetes Patients: A Comparative Analysis of Two Cohorts
Presenter: Sarah Richardson
Title: nPOD Viral Workgroup Introduction/Overview
Presenter: Alberto Pugliese
Title: nPOD Viral Workgroup – Update of Collaborative Plans and Ongoing Activities for IHC Studies
Presenter: Sarah Richardson
Title: nPOD Case 6052 – Focal MHC Class I Hyperexpression and Insulitis
Presenter: Ken Coppieters
Session 2: Autoantigens, T Cells and TCRs: Human Disease-specific Therapeutic Targets
Title: Defining Primary Trimolecular Complex for Type 1 Diabetes Mellitus
Presenter: George Eisenbarth
Title: In-situ Detection of Islet Antigen-specific CD8 T Cells in Insulitic Lesions of New-onset and Long-term Type 1 Diabetes Patients
Presenter: Ken Coppieters
Title: 454 Pyro-sequencing of T Cell Receptors Targeting Pancreatic Islets
Presenter: Maki Nakayama
Title: Monoclonal Expansions of TCR in a Diabetic Pancreas
Presenter: Mercè Martí
Session 3: Heterogeneity of Pancreas Pathology and Disease Mechanisms
Title: Expression and Regulation of Chemokines in Human Islets and Type 1 Diabetes
Presenter: Suparna Sarkar
Title: Down Regulation of Glucokinase and Mitochodrial ATP Synthase from Type 1 Organ Donors
Presenter: Yaíma Lightfoot
Title: Complement Activation in Type 1 Diabetes: Analysis of Pancreatic Tissue from nPOD Cases
Presenter: Patrick Rowe
Title: Adhesion Molecules on High Endothelial Venules of Pancreatic Lymph Nodes from Humans with Type 1 Diabetes
Presenter: Sara Michie
Session 4: From Genetics to Gene Expression in nPOD Tissues
Title: Regulation of Self-antigen Expression in Relation to Self-tolerance
Presenter: Alberto Pugliese
Title: Disease-dependent and Tissue-specific Changes in Gene Expression in Type 1 Diabetes
Presenter: Garry Fathman
Title: Identification of Extra-thymic Aire-expressing Cells (eTACs) in Human Tissue and Comparison between Type 1 Diabetic and Non-diabetic Controls
Presenter: Eileen McMahon
Session 5: What’s New at nPOD?
Title: What’s New at nPOD
Presenters: Martha Campbell-Thompson, Desmond Schatz, Clive Wasserfall, Jayne Moraski, Suzy Ball, Amy Wright, John Kaddis, Mark Atkinson, Carmen Retrum, Alberto Pugliese
Session 6: Emerging Technologies and Novel Research Avenues
Title: The Bone Marrow in Type 1 Diabetes – Feasibility of Flow Cytometric Analysis of nPOD Bone Marrow Specimens
Presenter: Paolo Madeddu
Title: The Role of IA-2 Extracellular Domain in Type 1 Diabetes Progression
Presenter: Michael Morran
Title: In Vitro Evaluation of Non-specific Binding of the Candidate Beta Cell Mass PET Probe (+) 18F-FP-DTBZ
Presenter: Paul Harris
Session 7: Pancreas and Beta Cell Biology
Title: The Pancreatic Duct Gland Compartment in Non-diabetic and Type 1 Diabetic Subjects
Presenter: Peter Butler
Title: Formation of a Baseline Pancreatic Beta Cell Mass in Humans is Completed Early in Life
Presenter: Chris Rhodes
Title: Beta Cells Persist in Some T1DM Pancreata without Attempted Evidence of Beta Cell Turnover nor Insulin-Glucagon Co-expression
Presenter: Dan Jacobson