Type 1 Diabetes Key Questions Working Groups
At nPOD, we are dedicated to pushing the boundaries of knowledge and believe that through collaboration we can address current issues in science of type 1 diabetes. For this purpose, we organized Key Questions working groups. These topics represent areas where we felt availability of nPOD tissues should be prioritized in order to address broad and important scientific questions relevant to the T1D research and care community. Our desire is that nPOD can inspire novel rigorous, organized, and collaborative activities using the bottom-up approach that nPOD has successfully employed in establishing collaborations in our community.
Is there a difference between type 1 diabetes in children and adults?
Prohormone processing defect in T1D pancreas
Role of the exocrine pancreas in T1D development
Translation studies to advance T1D therapies
Beta- and/or islet specific targets for a variety of studies
Understanding the diversity of T1D
Archives
nPOD Viral
nPOD-V represents a self-assembled collaborative effort with the goal of investigating the role of viruses in T1D through the study of nPOD samples.
nPOD Extracellular Matrix
The nPOD-ECM group is interested in the study of extra-cellular matrix components in the pathogenesis of T1D.
nPOD Omics
This group aims to establish standardized ‘omics data for each precious sample to better understand T1D pathogenesis.
nPOD Transplant
nPOD-T is aimed at scientifically researching human pancreatic tissue from organ donors who have had a pancreas transplant.
nPOD Autoimmunity
The nPOD-A group studies autoreactive T cells, B cells and other immune cell types with multiple goals.