nPOD West Slices/Islets Distribution Form Name(Required) Email(Required) Project Title(Required) Have you completed your nPOD approved project that relies on pancreas slices?(Required) Yes No If no, estimate the number of donors from which you would need to receive slices to complete your project. Please specify donor type, age, and other demographic information as applicable. Have the goals of your project shifted? If so, state what the new goals are and how many donors you would need. Have your current goals been reviewed and approved by the nPOD TPC? If not, you may have to submit an addendum. The soon to become active nPOD West will generate pancreas slices and isolate islets from the same donor. This will be done primarily for donors with T1D or AAB+. Would you also want to receive isolated islets from the same T1D or AAB+ donor from which slices can be provided in the future, or slices only, or islets only? If you are requesting islets in the future, state how many IEQs. Do you think it will be helpful to obtain both slices and islets from control donors? Have you signed up for the upcoming nPOD group focused on Key Question 4, In Vivo and In Vitro Translational Studies to Advance Therapies for T1D? It is expected that investigators working with slices or islets would at least engage in that group. If not, you are encouraged to sign up through this link. Please review the attached proposal to change the perfusion protocol so that basal glucose will be 5.5 mM instead of 3 mM, indicate whether this is OK for you and explain whether/when this can be implemented from your end. We believe this is beneficial, but we wanted to hear if there can be any potential downside.Finally, provide a short summary of your current project, summarize your results and anticipated projects needs and future directions (try to stay within 500 words).