Category: Current nPOD Projects

Modeling Autoimmune β-Cell Destruction in Human Pancreatic Slices, SliceChip, and Slice-in-ACE Platforms

Autoimmune β-cell loss in T1D occurs in a three-dimensional tissue context that current cell culture systems fail to replicate. HPSs preserve native islet-exocrine relationships and tissue architecture, providing a unique human platform to observe immune damage in real time. This revised application focuses on building controlled models of autoimmune β-cell injury, not on requesting rare […]