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1. (nPOD T1D) Pancreas from donors with type 1 diabetes age 40 years or younger with disease duration of 10 years or less. |
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2. (nPOD Aab+) Pancreas from Aab+ donor Age ≤ 30 years positive with at least 1 or more autoantibodies. |
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3. (nPOD DKA) Pancreas from non-diabetic donors 30 years in age or less, BMI less than 30 and cause of death related to Diabetic ketoacidosis (DKA), and/or has an HbA1C of 6.5% or higher. This criterion is to capture undiagnosed T1D donors. |
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4. (nPOD Slices) (Sun 0800- Fri 0800) Pancreas from donor 2-30 yo, non-diabetic, BMI 30 or less, normal amylase/lipase level, downtime less than 30 min, DCD okay. |
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Controls needed- Females 11-13 years and 19-30 years |
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Controls needed- Males 25- 30 years |
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Controls needed- Male and Female early age groups (0-10 years) |
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5. (nPOD adolescent T2D) Pancreas from donors 10-18 yo with type 2 diabetes or BMI greater than 35. |
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6. (CaRe-T1D Heart) Heart, kidneys, and peripheral vessels. (Calls Admin On-Call) |
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a. 18 years and older w/ T1D any duration, no illegal drug use, BMI <40 |
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b. (Daily 0800 - 2000) 18-65 yo w/ T2D any duration with documented cardiovascular disease (including dx during terminal admission), no illegal drug use, BMI <40 |
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c. (Daily 0800 - 2000) 18-65 years; Control donors, no illegal drug use, BMI <35 |
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7. (HANDEL-P) Pancreas from donors 2 to 4 years in age, non-diabetic donors. (islet isolation) |
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8. (HANDEL-I) Lung (right, left or bilateral), intestine, blood, spleen, and nodes from donors 26 weeks gestation to 12 years in age, non-diabetic donors. |
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9. (Tier 3 Pancreas) (Sun-Thurs from 0800-2000) Pancreas from donors 11-40 yo, BMI less than 30 (Calls Admin 2 On-Call) |