News & Events

Congratulations to the 16 investigators who received Breakthrough T1D funding for nPOD based studies. These awards began July 1, 2010 and funding for each project ranges between $50,000 and $210,000. nPOD now supports over 60 international investigators engaged in efforts to better understand the causes of type 1 diabetes and find ways to prevent and ultimately cure the disease. Below is a list of recently approved projects:

Breakthrough T1D Funded Investigators with New nPOD Projects:

Project Name: Identification of extrathymic Aire-expressing cells in human lymph nodes
PI: Mark Stuart Anderson, M.D., Ph.D., University of California, San Francisco

Project Name: Tracing effector and regulatory T-cell populations in type 1 diabetes
PI: Dolores Jaraquemada, Ph.D., Universitat Autonoma de Barcelona

Project Name: Risk of autoimmune diseases and human self-antigen expression
PI: Richard David Leslie, M.D, FRCP, University of London

Project Name: Sequencing the islet transcriptome
PI: Ivan Gerling, Ph.D., University of Tennessee, Memphis

Project Name: Evidence for increased numbers of stem cells in human T1D pancreas
PI: Leonard Harrison, D.Sc., Walter & Eliza Hall Institute of Medical Research

Project Name: Islet Resistance to T1D
PI: Clayton Mathews, Ph.D., University of Florida

Project Name: Detection of islet autoreactive CD8 T-cells in insulitis versus periphery
PI: Bart Roep, Ph.D., D.M., Leiden University

Project Name: Heparan sulfate levels mark the health status of human islet beta cells
PI: Charmaine Simeonovic, Ph.D., Australian National University

Project Name: Pathological changes associated with chronic RelB activation in T1D
PI: Ranjeny Thomas, MBBS, M.D., University of Queensland

Project Name: Extracellular matrix involvement in type I diabetes
PI: Thomas Wight, Ph.D., Benaroya Research Institute at Virginia Mason

Breakthrough T1D Funded Investigators with Established nPOD Projects

Project Name: Post-transcriptional regulation of pancreas-targeting nTreg cells
PI: Manuela Battaglia, Ph.D., San Raffaele Scientific Institute

Project Name: Age-dependent & tissue-specific changes in mRNA and miRNA expression in T1D
PI: Garry Fathman, M.D., Stanford University

Project Name: Development of T1D in humanized mice using tissues from autoimmune donors 
PI: Dale Greiner, Ph.D., University of Massachusetts

Project Name: Investigation of ß cells in islets, PLN and spleen in T1D
PI: Sally Kent, Ph.D., University of Massachusetts Medical Center

Project Name: Tissue-selective adhesion molecules in human T1D 
PI: Sara Michie, Ph.D., Standford University

Project Name: Direct replication of T cell receptors specific for type 1 diabetes
PI: Maki Nakayama, M.D., Ph.D., University of Colorado Health Science Center