nPOD Insulitis Case 6243 Featured on Cover of Diabetes

 

Research led by Dr. Martha Campbell-Thompson was featured on the cover of the March 2016 issue of Diabetes. Insulitis in a 13-year-old organ donor with type 1 diabetes for 5 years (nPOD 6243). Immune cell phenotypes in insulitic islets were determined by multi-immunofluoresence. An insulitic islet is shown with a lymphocytic infiltrate consisting of both CD3+ T cells (pink) and CD20+ B cells (green). α-Cells are detected with antiglucagon antibodies (yellow).