Category: Current nPOD Projects

Integrating functional and transcriptomic measurements in pancreatic islets with spatial resolution

Type 1 diabetes mellitus (T1D) is a complex autoimmune condition which is globally raising, it is influenced by genetic predisposition and environmental factors such as dietary changes and potential exposure to viruses or toxins. Single–cell methods have recently shown that endocrine islet cells are molecularly and functionally heterogeneous, and that cell–to–cell interactions within islets are […]