Category: Current nPOD Projects

De-differentiation of cryopreserved splenocytes to iPSC as an isogenic resource for differentiation to sc-islets. Addendum: De-differentiation of cryopreserved islet-derived T cell lines to iPSC as a resource for differentiation to sc-islets

In collaboration with the New York Stem Cell Foundation (NYSCF, see letter of collaboration), we will attempt de-differentiation of cryopreserved splenocytes to iPSC: this has not been attempted before to our knowledge. If successful, these iPSC may be differentiated into sc-islets and serve as an isogenic sources of sc-islets for interactions with the islet-derived T […]