12/15-lipoxygenase (12/15-LO) is an enzyme responsible for the metabolism of arachidonic acid to pro-inflammatory responses by immune cells in a variety of tissues, including pancreatic islets and fat tissues. Our extensive research has shown that type 1-like diabetes development is significantly diminished in the absence of 12/15-lipoxygenase. By using 12/15-LO deficient C57BL/6 mice, we were […]