Category: Current nPOD Projects

Maternal microchimerism in T1D pancreas

Maternal microchimerism (MMc) is acquired by an infant during pregnancy and these cells are maintained in some individuals for decades.  Encountering maternal antigens during pregnancy represents the first immunological challenge for the fetus although maternal cells are protected from detection by induction of suppressive fetal regulatory T cells. In type 1 diabetes increased levels of […]