Category: Current nPOD Projects

Dysregulation of molecular and cellular pathways in the pancreas during type 1 diabetes

Type 1 diabetes (T1D) is an autoimmune disease in which the insulin–producing β cells in the pancreas are selectively destroyed. Both genetic and environmental factors, such as viral infections, are implicated in the disease pathogenesis but how these factors contribute to the selective destruction of β cells at the cellular level remains unclear. Accumulating data […]