Category: Immunology

T cell autoreactivity, phenotype and function directly from islets of donors with recent onset type 1 diabetes (T1D) and from donors with islet-associated autoantibodies, but without clinical disease

The goal of this project is to further our understanding of the CD4 T cells and CD8 T cells that infiltrate the islets in autoantibody+ donors at risk for development of type 1 diabetes (T1D) and from donors with recent onset T1D. We will hand pick islets from digests of live pancreas slices from the […]