Category: Immunology

Human islet antigen trafficking to the pancreatic lymph node

Based on the mouse model of type 1 diabetes, it is believed that dendritic cells carry proteins from the pancreatic islets to the lymph nodes where they activate T cells to destroy the pancreatic islets. However, we find that unlike mice, human samples have no dendritic cells in their pancreatic islets. The aims we propose […]