Category: Immunology

Investigation of the sexual dimorphic phenotype of complosome expressing medullary thymic epithelial cells, and thymic B cells in type 1 diabetes

Quality control–the removal of immune cells that have the ability to attack our own tissues–is a central tenet of the immune system. In type 1 diabetes (T1D), impaired quality control in the thymus, leads to release of beta cell–reactive immune cells (called T cells) into the blood; such cells facilitate destruction of insulin–producing beta cells […]