Category: Beta Cell Physiology and Dysfunction

Regulation of Beta Cell Secretory Pathway Calcium Homeostasis in Type 1 Diabetes

Calcium plays a vital role in many processes that govern beta cell function, including the production, maturation, and regulated secretion of insulin. The fidelity of these processes depends on the maintenance of calcium subcompartments and their respective transmembrane gradients, which are organized at both the cellular and organelle level. Then endoplasmic reticulum, Golgi apparatus, and […]