Pancreatic Islet Cell Hyperexpression Pancreatic islet cell hyperexpression of HLA class-I was first observed from a small number of autopsy specimens from type 1 diabetes (T1D) patients in the 1980s, but in recent years, this notion was challenged as a potential artifact. Richardson et al. performed immunohistochemistery, immunofluorescence, and Affymetrix array analysis of RNA isolated […]