JDRF - Juvenile Diabetes Research Foundation International - Dedicated to finding a cure.

A quarterly e-newsletter for nPOD investigators, partners, and friends of the project. View the nPOD Newsletter archive.

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nPOD@pathology.ufl.edu

Metabolic and Developmental

Investigators in this group are using nPOD samples to try and understand the metabolic and developmental mechanisms associated with type 1 diabetes.

Alfred Bothwell Ihsane Marhfour
Clayton Mathews*
Hector DeLuca Sara Michie*
Decio Eizirik Margaret Morris*
Feyza Engin Jerry Nadler
Matthew Freeby Christopher Parish*
Ivan Gerling* Miquel Porta
Kathleen Gillespie Al Powers
Benjamin Glaser Shiva Reddy
Maria Grant Salvatore Sechi
Paul Harris Charmaine Simeonovic*
Kevan Herold Gerald Taborsky, Jr.
Gokhan Hotamisligil Akos Vertes
Sarah Howard Nao Wakae
Masanori Ichise Shannon Wallet
Amol Kavishwar J. Dennis Wilson*
Ruddy Leibel Baohui Xu
Kaiwen Ma Andrew Ziolkowski*

 

 

Alfred Bothwell, Ph.D.
Yale University

Project: Reconstitution of HHLS mice with bone marrow from patients with T1DM

Principal Investigator:
Kevan Herold, M.D.

 

 


 

 

University of Albany

Project: Persistent organic pollutants in the pancreatic tissue of people with and without diabetes

Co-Investigators:
Sarah Howard, M.S.
Miquel Porta, M.D., Ph.D.

 

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University of Wisconsin-Madison

Project: Vitamin D receptor in human insulitic pancreas

 

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Yuval Dor, Ph.D.
Hebrew University of Jerusalem

Project: Markers of stress in diabetic islets

Co-Investigator:
Benjamin Glaser, M.D.

 

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Universitè Libre de Bruxelles

Project: Characterization of beta cell ER stress markers in type 1 diabetes

Co-Investigator:
Ihsane Marhfour, Ph.D.

 

 

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Harvard University

Project: Examination of ER stress markers in type 1 diabetes samples in humans

Principal Investigator:
Gokhan Hotamisligil, M.D., Ph.D.

 

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Matthew Freeby, M.D.
Columbia University

Project: Determination of specific and non-specific binding of 18F-FP-DTBZ in whole pancreas homogenates obtained from controls and patients with longstanding type 1 diabetes

Principal Investigator:
Paul Harris, Ph.D.

 

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Ivan Gerling, Ph.D.*
University of Tennessee Health Science Center

Project: Sequencing the islet transcriptome

 

 

 

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University of Bristol

Project: Maternal microchimerism in T1D pancreas

 

 

 

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Hebrew University of Jerusalem

Project: Markers of stress in diabetic islets

Principal Investigator:
Yuval Dor, Ph.D.

 

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University of Florida

Project: Bone marrow progenitor cells (BMPCs) dysfunction in diabetes as mediated by reduced bioavailability of NO

 

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Columbia University

Project: Determination of specific and non-specific binding of 18F-FP-DTBZ in whole pancreas homogenates obtained from controls and patients with lonstanding type 1 diabetes

Co-Investigators:
Matthew Freeby, M.D.
Masanori Ichise, M.D.

 

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Yale University

Project: Reconstitution of HHLS mice with bone marrow from patients with T1DM

Co-Investigator:
Alfred Bothwell, Ph.D.

 

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Harvard University

Project: Examination of ER stress markers in type 1 diabetes samples in humans

Co-Investigator:
Feyza Engin, Ph.D.

 

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Sarah Howard, M.S.
University of Albany

Project: Persistent organic pollutants in the pancreatic tissue of people witha nd without diabetes

Principal Investigator:
David Carpenter, M.D.

 

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Masanori Ichise, M.D.
Columbia University

Project: Determination of specific and non-specific binding of 18F-FP-DTBZ in whole pancreas homogenates obtained from controls and patients with longstanding type 1 diabetes

Principal Investigator:
Paul Harris, Ph.D.

 

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Amol Kavishwar, Ph.D.
Massachusetts General Hospital

Project: In vivo imaging of islets

Principal Investigator:
Anna Moore, Ph.D.

 

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Rudy Leibel, M.D.
Columbia University

Project: E-cadherin mediates developmental effects on the proliferation and the function of ß-cells in the islet of Langerhans

Co-Investigator:
Nao Wakae, M. Phil.

 

 

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Kaiwen Ma, Ph.D.
Eastern Virginia Medical School

Project: 12/15 Lipoxygenase expression in type 1 diabetes

Principal Investigator:
Jerry Nadler, M.D.

 

 

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Ihsane Marhfour, Ph.D.
Universitè Libre de Bruxelles

Project:Characterization of beta cell ER stress markers in type 1 diabetes

Principal Investigator:
Decio Eizirik, M.D., Ph.D.

 

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University of Florida

Project: Islet resistance to T1D

 

 

 

 

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Sara Michie

Sara Michie, M.D.*
Stanford University

Project: Tissue-selective adhesion molecules in type 1 diabetes

Co-Investigator:
Baohui Xu, M.D., Ph.D.

 

 

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Anna Moore, Ph.D.
Massachusetts General Hospital

Project: In vivo imaging of islets

Co-Investigator:
Amol Kavishwar, Ph.D.

 

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Margaret Morris, Ph.D.*
Eastern Virginia Medical School

Project: 12/15 Lipoxygenase expression in type 1 diabetes

Principal Investigator:
Jerry Nadler, M.D.

 

 

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Jerry Nadler

Eastern Virginia Medical School

Project: 12/15 Lipoxygenase Expression in Type 1 Diabetes

Co-Investigators:
Margaret Morris, Ph.D.
Kaiwen Ma, Ph.D.

 

 

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Australian National University

Project: Heparan sulfate levels mark the health status of human islet ß cells

Principal Investigator:
Charmaine Simeonovic, Ph.D.

 

 

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Miquel Porta, M.D., Ph.D.
University of Albany

Project: Persistent organic pollutants in the pancreatic tissue of people with and without diabetes

Principal Investigator:
David Carpenter, M.D.

 

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Vanderbilt University

Project: Pancreatic islet biology and vascularization

 

 

 

 

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Shiva Reddy, Ph.D., M.Sc.
The University of Auckland, New Zealand

Project: Immunohistochemical identification of molecular markers of oxidative and nitrosative stress in ß-cells during the early stages of human type 1 diabetes mellitus

 

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Salvatore Sechi, Ph.D.
George Washington University

Project: Molecular profile of the pancreatic tissue of long-standing type 1 diabetic patients

Co-Investigator:
Akos Vertes, Ph.D.

 

 

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Australian National University

Project: Heparan sulfate levels mark the health status of human islet ß cells

Co-Investigators:
Christopher Parish, Ph.D.
J. Dennis Wilson, M.D.
Andrew Ziolkowski, Ph.D.

 

 

 

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taborsky

University of Washington

Project: Glucagon secretion and islet neuropathy

 

 

 

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George Washington University

Project: Molecular profile of the pancreatic tissue of long-standing type 1 diabetic patients

Principal Investigator:
Salvatore Sechi, Ph.D.

 

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Nao Wakae, M. Phil.
Columbia University

Project: E-cadherin mediates developmental effects on the proliferation and the function of ß-cells in the islet of Langerhans

Principal Investigator:
Rudy Leibel, M.D.

 

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University of Florida

Project: Role of mucosal epithelium in autoreactivity

 

 

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J. Dennis Wilson, M.D.*
Australian National University

Project: Heparan sulfate levels mark the health status of human islet ß cells

Prinicpal Investigator:
Charmaine Simeonovic, Ph.D.

 

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Baohui Xu, M.D., Ph.D.
Stanford University

Project: Tissue-selective adhesion molecules in human type 1 diabetes

Principal Investigator:
Sara Michie, M.D.

 

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Andrew Ziolkowski*
Australian National University

Project: Heparan sulfate levels mark the health status of human islet ß cells

Principal Investigator:
Charmaine Simeonovic, Ph.D.

 

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*These investigators have received funding from the Juvenile Diabetes Research Foundation (JDRF).